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Rinse mouth. Remove contaminated clothes. Current as of October 03, 2022 | Updated by FindLaw Staff. Lindane in soil can leach to surface and even ground water and can bioaccumulate in the food chain. 0000001244 00000 n In 2003, the FDA published a safety analysis of adverse events reported in association with the use of lindane medications received through its adverse event monitoring system (AERS database) between from 1974 through 2002. (2) On a combination packaging containing a marine pollutant, other than a severe marine pollutant, in inner packagings each of which contains: (i) 5 L (1.3 gallons) or less net capacity for liquids; or. Code of Federal Regulations Title 49. This produces toxic and corrosive fumes including hydrogen chloride and trichlorobenzenes (see ICSCs 0344, 1049 and 1222). In the 1940s, lindane was registered with the U.S. Department of Agriculture (USDA), and in 1951 it was approved by the U.S. Food and Drug Administration (FDA) for medical use in the treatment of scabies, head lice and pubic lice (crabs). The mark may be displayed in black lettering on a square-on-point configuration having the same outside dimensions as a placard; or. In 2001, the Environmental Protection Agencys Cancer Assessment Review Committee for lindane downgraded the carcinogenic classification of lindane from possible to suggestive evidence, concluding that the data did not support the need for further study of the carcinogenic risks in humans. 0000004014 00000 n Lindane (Ref: OMS 17) - University of Hertfordshire Animal tests show that this substance possibly causes toxicity to human reproduction or development. eCFR :: 49 CFR 172.322 -- Marine pollutants. Lindane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABAA receptor-chloride channel complex at the picrotoxin binding site. WebLindane is a persistent organic pollutant: it is relatively long-lived in the environment, it is transported long distances by natural processes like global distillation, and it can Lindane persists in the environment and bioaccumulates as an organochlorine pesticide and can pose risks to ecological environments and human Further see Ingestion. 0000001327 00000 n