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Chlamydia trachomatis is a gram-negative bacterium that infects the columnar epithelium of the cervix, urethra, and rectum, as well as nongenital sites. However, perinatally transmitted C. trachomatis infection of the nasopharynx, urogenital tract, and rectum can persist for 23 years (see Sexual Assault or Abuse of Children). Chlamydia trachomatis-Neisseria gonorrhoeae RNA, Urine. Systematic review of randomized controlled trials, Consensus opinion from clinical guidelines, High certainty of substantial net benefit. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Even when symptoms occur, they're often mild. WebChlamydia trachomatis has been identified as a causative agent for acute urethral syndrome, defined as acute dysuria and frequent urination in women whose voided urine Early-stage Chlamydia trachomatis infections often cause few symptoms. Method Name Transcription Mediated Amplification NY State Available Yes Reporting Name Patients who are pregnant should be tested for cure three weeks after treatment for chlamydial infection. Self-collected rectal swabs are a reasonable alternative to clinician-collected rectal swabs for C. trachomatis screening by NAAT, especially when clinicians are not available or when self-collection is preferred over clinician collection. WebInfection with C. trachomatis is common in selected geographic areas ( 911 913 ), although M. genitalium is often the sole pathogen. They help us to know which pages are the most and least popular and see how visitors move around the site. Women can develop reactive arthritis, but the male-to-female ratio is 5:1. Chlamydia trachomatis is part of the chlamydophila genus. As part of this approach, doxycycline is provided as initial empiric therapy, which reduces the organism load and facilitates organism clearance, followed by macrolide-sensitive M. genitalium infections treated with high-dose azithromycin; macrolide-resistant infections are treated with moxifloxacin (964,965). Chlamydia trachomatis RNA As an alternative, prevention efforts should focus on prenatal screening for C. trachomatis, including. Previous evidence indicates that the liquid-based cytology specimens collected for Pap smears might be acceptable specimens for NAAT, although test sensitivity using these specimens might be lower than that associated with use of cervical or vaginal swab specimens (799); regardless, certain NAATs have been cleared by FDA for use on liquid-based cytology specimens. If M. genitalium is detected, a regimen of moxifloxacin 400 mg orally once daily for 14 days has been effective in eradicating the organism. NAATs are not cleared by FDA for detecting chlamydia from nasopharyngeal specimens, and clinical laboratories should verify the procedure according to CLIA regulations (553). Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Providers should provide patients with written educational materials to give to their partners about chlamydia, which should include notification that partners have been exposed and information about the importance of treatment.